Best Tools for Gut Health & Weight Loss | Dr. Chris Thompson

Sep 21, 2026 · 2h 28m

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EP · Huberman Lab · Best Tools for Gut Health & Weight Loss | Dr. Chris Thompson2:28:08

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asr · 29,732 words · docs

0:00There's all sorts of evidence that if you don't have a lot of fiber, your microbiome is not healthy.

0:05Feed your microbes, you know, they need to be fed.

0:07And what they eat is fiber.

0:09Okay, that's what you want them eating.

0:10You want them eating fiber.

0:12And if you're not feeding them fiber, they'll eat your mucus layer.

0:15Okay.

0:15And we already talked about how thin that barrier is.

0:17And all of a sudden they start eating your mucus layer.

0:20They're not producing the butyrate you need and the butyrate's needed to maintain the tight junctions.

0:24So there's layers to this.

0:26It's like a snowball effect that if you're not feeding those microbiome and keeping it healthy, you're going to run into all sorts of trouble.

0:35Welcome to the Huberman Lab Podcast, where we discuss science and science-based tools for everyday life.

0:44I'm Andrew Huberman, and I'm a professor of neurobiology and ophthalmology at Stanford School of Medicine.

0:50My guest today is Dr.

0:51Chris Thompson.

0:52Dr.

0:52Chris Thompson is a professor of medicine at Harvard Medical School.

0:56He is also the chief of interventional gastroenterology at Mass General Brigham in Boston.

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