Antidepressants Explained: Benefits, Risks, and Alternatives for Depression | Dr. James Greenblatt

Jun 3, 2026 · 55 min

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Transcript

asr · 9,185 words · docs
0:00Let's talk about antidepressants, what percent are they affected for, who they're affected for, and where are we failing with these medications?
0:06For too many years, the psychiatric community completely ignored what happens when you stop these medications.
0:11I call it withdrawal, they call it discontinuation syndrome, and it was just kind of eye-opening when I had two people stop the same medicine.
0:19It was Selexa, and one person did it fine, and the next one had these intractable, you know, brain zaps and suicidal thoughts.
0:28And I realized, well, it's not the medicine, it's what's going on in that individual.
0:33And once we do the functional testing, we replete the D and the B12 or the amino acids, we can safely withdraw someone from these antidepressants.
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