#398 ‒ AMA #86: GLP-1 RAs and muscle loss: new data, better questions, and how to preserve muscle during weight loss

Jun 29, 2026 · 9h 1m

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asr · 1,639 words · docs
0:10Hey everyone, welcome to a sneak peek, Ask Me Anything, or AMA episode of the Drive podcast.
0:16I'm your host, Peter Attia.
0:17At the end of this short episode, I'll explain how you can access the AMA episodes in full, along with a ton of other membership benefits we've created.
0:25Or you can learn more now by going to peteratiamd.com forward slash subscribe.
0:30So without further delay, here's today's sneak peek of the Ask Me Anything episode.
0:39Welcome to Ask Me Anything AMA episode 86.
0:43In today's AMA, we're going to look at the effects of GLP-1 receptor agonists.
0:47So these are drugs like Ozempic, Wogovi, and Zeppbound.
0:50But specifically, we're going to look at the impact they have on muscle.
0:54We're going to talk about how much lean mass people actually lose on these drugs and how that compares to weight loss by any other means.
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