Podcasts / All-In with Chamath, Jason, Sacks & Friedberg

Bryan Johnson: I Just Took the Most Powerful Dose of DMT in the World... Here's What It Was Like

Mar 26, 2026 · 2 min

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EP · All-In with Chamath, Jason, Sacks & Friedberg · Bryan Johnson: I Just Took the Most Powerful Dose of DMT in the World... Here's What It Was Like2:13

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asr · 6,953 words · docs

0:00Brian Johnson, thanks for being here.

0:01Yeah, it's good to see you.

0:02How are you feeling?

0:03Maybe just share with us what you did a few days ago.

0:05Yeah, I did a 5-MEO DMT, which is the most powerful psychedelic on the planet.

0:13Somewhere between 5 and 10 times more powerful than DMT.

0:17And so, yeah, so it's been 48 hours.

0:21I'm still learning how to talk about it.

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0:54Before we get into your experience, why did you choose to do it?

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0:58One, mostly as a longevity experiment.

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