How Mitochondria Control Your Metabolism | Dr. Jared Rutter

Sep 7, 2026 · 2h 4m · YouTube

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0:00There's a widely accepted hypothesis that mitochondria with excess energy leads to problems.

0:08Many people that are listening have probably heard of reactive oxygen species.

0:12This is forms of oxygen that become reactive and end up spinning out and damaging proteins and nucleic acids.

0:20And I think it is widely accepted that one of the contributors to that is mitochondria that have too much energy.

0:28Basically, the form that energy takes when it's extracted from the food we eat and before it's converted to ATP is powering the mitochondria.

0:37And when that mitochondria is overpowered, that leads to a state that is very susceptible to generation of these reactive species that end up damaging our genome, creating mutations and damaging proteins and creating many of the problems that we see.

0:51Welcome to the Huberman Lab Podcast, where we discuss science and science-based tools for everyday life.

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