Matt McCusker, Andrew Huberman & Tom Segura - Mostly Wise #1 - #1102

May 25, 2026 · 2h 42m · YouTube

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asr · 34,118 words · docs
0:00I keep seeing tweets about how everyone should be taking erectile dysfunction medication.
0:03Is that true?
0:04Low-grade, whatever.
0:05Yeah, like low-grade.
0:07So, tadalophil, which is the generic name for C.
0:11alice, was developed first as a prostate health drug.
0:14And then people took more of it and realized that at higher dosages, it can be effective for erectile dysfunction.
0:20But low dose is good for prostate health.
0:22Low dose, like 2.5 to 5 milligrams per day, is very helpful for perfusion of the prostate.
0:28And also, it causes vasodilation in the brain.
0:32So things like strokes.
0:33I mean, you want blood flow, right?
0:35You don't want excessive blood flow.
0:36You've got a headache from it.
0:38But our chair of male sexual health and urology at Stanford, Mike Eisenberg, he came on the podcast and he said pretty much every male over 40 or so should be taking about 2.5 to 5 milligrams per day.
0:49Does it still get you pretty hard too?
0:51It definitely will improve.
0:53Just curious.
0:56It will definitely notch up erectile strength.
0:59But unlike some health people out there, I'm not using the calipers to measure the strength.
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